Bioferment 20

Useful to rebalance the bacterial flora

It contains no gluten, lactose and milk derivatives, dyes, GMOs, sweeteners.


BIOFERMENT

Bioferment-linea

Components and main activities

The two products of the line, vials, and capsules, contain a mixture of five strains of lactic acid bacteria, defined probiotics.

The positive effects for humans attributed to the metabolic activity of probiotic microorganisms are:

  • Synthesize antimicrobial substances
  • Stimulate and modulate the immune system’s response
  • Improving and stabilizing intestinal barrier function
  • Synthesize vitamins.

The microorganisms of BIOFERMENT are produced according to the important features of the microbial formulation, such as:

a) the human origin of all organisms;

b) the complex nature of the mixture that simulates the heterogeneous composition of the intestinal microflora;

c) the high dose of viable cells present per dose, which ensures at the intestinal level an amount of viable microorganisms sufficient for a rapid colonization of the intestinal mucosa;

d) the presence of the 4 non-sporifying strains, provided with a double surface protection patented by the manufacturer, which is insoluble in an acidic environment and soluble at pH 6.5 (pH of the duodenum), and that isolates from the action of bile salts, so the cells of lactobacilli and bifidobacteria used may arrive intact to the duodenum, hydrate to activate cellular function and be well suited to lush growth in the colon, from where they exert their beneficial effects; the presence of one strain belonging to Bactolacillus sporegenes defined Lacotbacillus acid is able to germinate in the intestine and is extremely resistant to high temperatures;

e) a high biological stability in time; this stability is promoted by the search for an excipient with low aw value (free water), this parameter is respected at all times in the production cycle, which takes place in conditions of controlled temperature and humidity and preservation of the product. The result is an increase in stability and viability over time and in the conditions of use;

f) a high capacity of all strains used to resist the acid pH of the gastric tract.

The mixture of probiotics of BIOFERMENT consists of the following five strains of lactobacillus and bifidobacteria:

  • Lactobacillus acidophilus
  • Bifidobacterium lactis
  • Lactobacillus plantarum
  • Lactobacillus paracasei
  • Lactobacillus acid

Specifically, each of them has a well-defined and demonstrated function.

The two products of the line, vials, and capsules, contain a mixture of five strains of lactic acid bacteria, defined probiotics.

The positive effects for humans attributed to the metabolic activity of probiotic microorganisms are:

  • Synthesize antimicrobial substances
  • Stimulate and modulate the immune system’s response
  • Improving and stabilizing intestinal barrier function
  • Synthesize vitamins.

The microorganisms of BIOFERMENT are produced according to the important features of the microbial formulation, such as:

a) the human origin of all organisms;

b) the complex nature of the mixture that simulates the heterogeneous composition of the intestinal microflora;

c) the high dose of viable cells present per dose, which ensures at the intestinal level an amount of viable microorganisms sufficient for a rapid colonization of the intestinal mucosa;

d) the presence of the 4 non-sporifying strains, provided with a double surface protection patented by the manufacturer, which is insoluble in an acidic environment and soluble at pH 6.5 (pH of the duodenum), and that isolates from the action of bile salts, so the cells of lactobacilli and bifidobacteria used may arrive intact to the duodenum, hydrate to activate cellular function and be well suited to lush growth in the colon, from where they exert their beneficial effects; the presence of one strain belonging to Bactolacillus sporegenes defined Lacotbacillus acid is able to germinate in the intestine and is extremely resistant to high temperatures;

e) a high biological stability in time; this stability is promoted by the search for an excipient with low aw value (free water), this parameter is respected at all times in the production cycle, which takes place in conditions of controlled temperature and humidity and preservation of the product. The result is an increase in stability and viability over time and in the conditions of use;

f) a high capacity of all strains used to resist the acid pH of the gastric tract.

The mixture of probiotics of BIOFERMENT consists of the following five strains of lactobacillus and bifidobacteria:

  • Lactobacillus acidophilus
  • Bifidobacterium lactis
  • Lactobacillus plantarum
  • Lactobacillus paracasei
  • Lactobacillus acid

Specifically, each of them has a well-defined and demonstrated function.

It is the most represented species in the human gut (also present in other parts of the body such as the oral cavity and the vagina), and for this reason present in appreciable percentage within the mixture of the title compound. The experimental and clinical studies support the quality of this strain in terms of:

  • effective vitality in the gut
  • immuno-stimulant / balancing activities
  • reduced survival of pathogenic forms
  • restores the correct balance of intestinal flora.

It is the most represented species in the human gut (also present in other parts of the body such as the oral cavity and the vagina), and for this reason present in appreciable percentage within the mixture of the title compound. The experimental and clinical studies support the quality of this strain in terms of:

  • effective vitality in the gut
  • immuno-stimulant / balancing activities
  • reduced survival of pathogenic forms
  • restores the correct balance of intestinal flora.

It differs from other bifidobacteria because, thanks to its particular resistance to the action of the bile and its ability to tolerate oxygen, is able to colonize the upper small intestine. Moreover, unlike the Lactobacillus Acidophilus, it has different resistance patterns to antibiotics compensating for any sensitivity to Acidophilus to that effect (present in greater proportion within the mixture, thanks to the properties listed above). Several studies have shown the various effects of this probiotic microorganism in terms of:

  • effective vitality in the intestine
  • rebalancing the immune system
  • reducing the survival of pathogenic forms.

It differs from other bifidobacteria because, thanks to its particular resistance to the action of the bile and its ability to tolerate oxygen, is able to colonize the upper small intestine. Moreover, unlike the Lactobacillus Acidophilus, it has different resistance patterns to antibiotics compensating for any sensitivity to Acidophilus to that effect (present in greater proportion within the mixture, thanks to the properties listed above). Several studies have shown the various effects of this probiotic microorganism in terms of:

  • effective vitality in the intestine
  • rebalancing the immune system
  • reducing the survival of pathogenic forms.

It is one of the commensal species of the human gut. It belongs to the group of lactic acid bacteria implementing heterolactic fermentation, and is often isolated from plant material and fermented foods. Several studies have shown the various effects of this probiotic microorganism in terms of:

  • contribution to the proper balance of intestinal flora
  • effective vitality in the intestine
  • rebalancing the immune system
  • reducing the survival of pathogenic forms.

It is one of the commensal species of the human gut. It belongs to the group of lactic acid bacteria implementing heterolactic fermentation, and is often isolated from plant material and fermented foods. Several studies have shown the various effects of this probiotic microorganism in terms of:

  • contribution to the proper balance of intestinal flora
  • effective vitality in the intestine
  • rebalancing the immune system
  • reducing the survival of pathogenic forms.

It represents one of the main allochthonous probiotics that colonize the intestinal tract in a transitory manner and should be integrated with the daily diet to promote normal intestinal function and vitality. Several studies have shown the various effects of this probiotic microorganism in terms of:

  • contribution to the proper balance of intestinal flora
  • effective vitality in the intestine
  • rebalancing the immune system
  • reducing the survival of pathogenic forms.

It represents one of the main allochthonous probiotics that colonize the intestinal tract in a transitory manner and should be integrated with the daily diet to promote normal intestinal function and vitality. Several studies have shown the various effects of this probiotic microorganism in terms of:

  • contribution to the proper balance of intestinal flora
  • effective vitality in the intestine
  • rebalancing the immune system
  • reducing the survival of pathogenic forms.

Spore-forming nature. Resistant to temperatures of over 120 ° C for 20 ‘. It is resistant to bile acids. Returns vegetative cells to enteric physiological conditions. It does not ferment. It is not a gas producer. Like many spore-forming bacteria, it has a marked tendency to germination and adhesion to the intestinal environment, as shown by several scientific studies, including the work of Hashimo K. Et, published in 1964 in New Drugs and Clinics. The acidic environment of the stomach is favorable because, undermining the structure of the capsule contributes to the transformation of the spore in vegetative cell. This transformation will end on the mucosa of the small intestine where the proliferation begins, copying itself every 30 minutes for an average total of 2/4 hours after ingestion. The microorganism is cleared very slowly and can be found in feces up to 7 days after the last dose; laboratory evidence show that the incubation in microaerophilic and anaerobic conditions does not affect the germination as well as for other non-anaerobic lactobacilli.

Spore-forming nature. Resistant to temperatures of over 120 ° C for 20 ‘. It is resistant to bile acids. Returns vegetative cells to enteric physiological conditions. It does not ferment. It is not a gas producer. Like many spore-forming bacteria, it has a marked tendency to germination and adhesion to the intestinal environment, as shown by several scientific studies, including the work of Hashimo K. Et, published in 1964 in New Drugs and Clinics. The acidic environment of the stomach is favorable because, undermining the structure of the capsule contributes to the transformation of the spore in vegetative cell. This transformation will end on the mucosa of the small intestine where the proliferation begins, copying itself every 30 minutes for an average total of 2/4 hours after ingestion. The microorganism is cleared very slowly and can be found in feces up to 7 days after the last dose; laboratory evidence show that the incubation in microaerophilic and anaerobic conditions does not affect the germination as well as for other non-anaerobic lactobacilli.

BIOFERMENT takes on the role of a symbiotic because the probiotic component is associated with defined prebiotic substances that are not adsorbed in the upper part of the intestine but are available to be fermented by bacteria in the gut. The main property of prebiotics is to stimulate the development of bifidobacteria and lactobacilli, reducing the growth of pathogens, contributing to balance in the production of short-chain fatty acids and lactic acid and promoting proper bowel function (physiological laxative). Short chain carbohydrates with recognized prebiotic effects are represented by fructooligosaccharides, galacto-oligosaccharides, gluco-oligosaccharides, xylo-oligosaccharides and inulin. With the product BIOFERMENT, which happens to be a symbiotic supplement, the results reported in the scientific literature were considered for the choice of prebiotic. This choice therefore fell on arabin-galacto-oligo-saccharide to make another very important improvement just with respect to the realization of synergistic actions of the prebiotic substance such as its slow fermentation, which decreases the side effects of gas and bloating present with other polysaccharides, its stability at low pH and at room temperature, which makes this polysaccharide easily used for drinks and its important capacity of balanced response to stress by improving the weak aspects of the immune system and suppressing the negative aspects that derive from particular conditions.

BIOFERMENT takes on the role of a symbiotic because the probiotic component is associated with defined prebiotic substances that are not adsorbed in the upper part of the intestine but are available to be fermented by bacteria in the gut. The main property of prebiotics is to stimulate the development of bifidobacteria and lactobacilli, reducing the growth of pathogens, contributing to balance in the production of short-chain fatty acids and lactic acid and promoting proper bowel function (physiological laxative). Short chain carbohydrates with recognized prebiotic effects are represented by fructooligosaccharides, galacto-oligosaccharides, gluco-oligosaccharides, xylo-oligosaccharides and inulin. With the product BIOFERMENT, which happens to be a symbiotic supplement, the results reported in the scientific literature were considered for the choice of prebiotic. This choice therefore fell on arabin-galacto-oligo-saccharide to make another very important improvement just with respect to the realization of synergistic actions of the prebiotic substance such as its slow fermentation, which decreases the side effects of gas and bloating present with other polysaccharides, its stability at low pH and at room temperature, which makes this polysaccharide easily used for drinks and its important capacity of balanced response to stress by improving the weak aspects of the immune system and suppressing the negative aspects that derive from particular conditions.

  • Arabin-galacto-oligosaccharides derived from larch
  • Extract of Aloe vera
  • Carrageenan
  • Glucans from the cell walls of lysed cells of Saccharomyces cerevisiae.

This formulation allows the maintenance of a high viability of the probiotics when the same are taken orally. It is known that the crucial passage of a composition containing lactic acid bacteria is represented by the gastric transit. The digestive system is characterized by environments (stomach, small intestine and large intestine) with completely different chemical, physical and biological properties. The special formulation of BIOFERMENT overcomes the problem of the viability of microorganisms in the gastric transit with four different strategies: a) the administration of the product immediately after the meal because, in these conditions, the buffering effect of the partially digested food makes the gastric environment less acid and the pH is changed from 1-2 to about 4-5; b) it takes strains of human origin, which present a particular resistance to gastric juice and bile acids. Bacterial strains isolated from man are certainly able to survive in the gastrointestinal tract more effectively than can strains isolated from non-human sources, because these bacteria are already well adapted to grow in that kind of ecosystem. Therefore, probiotic strains of human origin are able to colonize rapidly and in an optimal manner and permanently in the human gut; c) in the phase of lyophilization 4 strains are covered with a protective layer by a process patented by the supplying company; the 5th strain, endospore, is naturally resistant to the acidic environment and of course it is equally capable of colonizing the intestine. In the formulation of the product between the prebiotics are also present Aloe extract and carrageenan, which in the gastric acid jellify by covering microbial cells with a protective layer. During the intestinal transit, for the increase in the pH, the gel melts slowly, giving a viscous phase which helps to decrease the speed of transit of probiotics and to improve their adhesion to the intestinal villi. d) the quantity of sugars in the colon is minimal and does not allow the resident microbial flora to be able to adequately develop. To provide a nutritional benefit to probiotics, the formula is different polysaccharides resistant to gastric digestion, reaching the colon unchanged, where they are metabolized by probiotics, which thanks to this nutritional relationship, develop and produce antimicrobial substances beneficial for the body such as bacteriocins, lactic acid, acetic acid and butyric acid.

  • Arabin-galacto-oligosaccharides derived from larch
  • Extract of Aloe vera
  • Carrageenan
  • Glucans from the cell walls of lysed cells of Saccharomyces cerevisiae.

This formulation allows the maintenance of a high viability of the probiotics when the same are taken orally. It is known that the crucial passage of a composition containing lactic acid bacteria is represented by the gastric transit. The digestive system is characterized by environments (stomach, small intestine and large intestine) with completely different chemical, physical and biological properties. The special formulation of BIOFERMENT overcomes the problem of the viability of microorganisms in the gastric transit with four different strategies: a) the administration of the product immediately after the meal because, in these conditions, the buffering effect of the partially digested food makes the gastric environment less acid and the pH is changed from 1-2 to about 4-5; b) it takes strains of human origin, which present a particular resistance to gastric juice and bile acids. Bacterial strains isolated from man are certainly able to survive in the gastrointestinal tract more effectively than can strains isolated from non-human sources, because these bacteria are already well adapted to grow in that kind of ecosystem. Therefore, probiotic strains of human origin are able to colonize rapidly and in an optimal manner and permanently in the human gut; c) in the phase of lyophilization 4 strains are covered with a protective layer by a process patented by the supplying company; the 5th strain, endospore, is naturally resistant to the acidic environment and of course it is equally capable of colonizing the intestine. In the formulation of the product between the prebiotics are also present Aloe extract and carrageenan, which in the gastric acid jellify by covering microbial cells with a protective layer. During the intestinal transit, for the increase in the pH, the gel melts slowly, giving a viscous phase which helps to decrease the speed of transit of probiotics and to improve their adhesion to the intestinal villi. d) the quantity of sugars in the colon is minimal and does not allow the resident microbial flora to be able to adequately develop. To provide a nutritional benefit to probiotics, the formula is different polysaccharides resistant to gastric digestion, reaching the colon unchanged, where they are metabolized by probiotics, which thanks to this nutritional relationship, develop and produce antimicrobial substances beneficial for the body such as bacteriocins, lactic acid, acetic acid and butyric acid.